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Of the 2—4 mg of copper ingested daily with our food, 0. Clinical manifestations of hypocupraemia are a sensorimotor polyneuropathy; damage to the optic nerve as well as the myelon with sensory ataxia and pyramidal tract signs 8082 The occurrence of different forms of anaemia varies greatly.
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Classification and differential diagnosis of Wilson’s disease
Wikispecies Free species directory. Ceruloplasmin is physiologically low in infancy It is located in the intestine on the basal membrane of the enterocytes and responsible for copper absorption 2349 Every cloud has a silver lining.
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Disrupted copper-dependent enzymes in the CNS and connective tissue metabolism are responsible for the symptomology. Adaptor proteins AP regulate the transport of transmembrane proteins and the clathrin-coated vesicles between Golgi apparatus, endosomes and plasma membrane.
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